Centennial Football
| Date | Opponent | Results |
| Fri 8/26/22 | Indianola | L 20-26 |
| Fri 9/2/22 | at Ankeny | L 10-17 |
| Fri 9/9/22 | at Waukee | W 31-6 |
| Fri 9/16/22 | Cedar Falls | W 28-14 |
| Fri 9/23/22 | Sioux City East | W 31-28 |
| Fri 9/30/22 | at Urbandale | |
| Fri 10/7/22 | Waukee Northwest | |
| Fri 10/14/22 | at Southeast Polk | |
| Fri 10/21/22 | Des Moines East | |
| Fri 10/28/22 | Class 5A First Round | |
| Fri 11/4/22 | Class 5A Quarterfinals | |
| Fri 11/11/22 | Class 5A Semifinals at UNI-Dome | |
| Fri 11/18/22 | Class 5A Championship at UNI-Dome |
W