Centennial Boys’ Basketball
| Date | Opponent | Result |
| Tue 11/30/21 | Southeast Polk | L 49-54 |
| Fri 12/3/21 | Fort Dodge | W 79-46 |
| Tue 12/7/21 | at Des Moines Lincoln | W 72-66 (OT) |
| Tue 12/14/21 | at Johnston | L 71-92 |
| Thu 12/16/21 | at Mason City | W 89-47 |
| Tue 12/21/21 | at Waukee Northwest | L 58-80 |
| Tue 1/4/22 | Waukee Northwest | L 50-72 |
| Fri 1/7/22 | Ames | L 38-58 |
| Tue 1/11/22 | Ankeny | L 48-58 |
| Tue 1/18/22 | Des Moines Hoover | W 50-41 |
| Thu 1/20/22 | at Fort Dodge | W 76-33 |
| Fri 1/21/22 | Mason City | W 89-82 (2 OT) |
| Tue 1/25/22 | at Des Moines East | W 67-44 |
| Fri 1/28/22 | at Marshalltown | W 80-75 |
| Sat 1/29/22 | Davenport West | W 69-59 |
| Fri 2/4/22 | at Ames | L 37-44 |
| Tue 2/8/22 | Dowling Catholic | W 49-40 |
| Fri 2/11/22 | at Ankeny | L 79-81 (OT) |
| Mon 2/14/22 | Marshalltown | W 76-71 |
| Tue 2/15/22 | at Des Moines North | W 76-48 |
| Fri 2/18/22 | at Urbandale | L 51-55 (OT) |
| Fri 2/25/22 | Class 4A substate semifinal, vs. Des Moines Hoover | L 37-49 |